Skincare products containing ingredients derived from Centella asiatica, more commonly known as Cica, have become popular as anti-aging remedies, moisturizers, anti-inflammatory drugs, and in treating scars, wounds, and atopic dermatitis, among other skin conditions.1-7 Cica has been used in homeopathy for centuries to treat a variety of ailments.2,6 Due to the many purported benefits of its skincare formulations, we examined the mechanisms of cica and reviewed the existing literature in order to shed more light on its role in dermatology. (SKINmed. 2022;20:94-96).