Clinical clues to identify patients with ocular rosacea - a Germany-wide epidemiologic analysis

Int J Dermatol. 2022 Jul;61(7):880-885. doi: 10.1111/ijd.16235. Epub 2022 May 17.

Abstract

Background and objectives: Ocular rosacea is a special manifestation of rosacea with unknown etiology. Eye involvement in rosacea patients is surprisingly common; however, it is often underdiagnosed, resulting in inappropriate treatment. We aimed to provide an updated epidemiologic perspective on ocular rosacea in Germany to improve patient care.

Patients and methods: Data of 777 rosacea patients were assessed using a detailed online questionnaire regarding ocular and skin symptoms, previous dermatological and ophthalmological consults, presence of type 1 hypersensitivities, and Demodex testing. All data were statistically analyzed.

Results: Most patients reported ocular symptoms (399/777, 51.4%), including red eyes (179/399, 44.9%), itching (187/399, 46.9%), sty or chalazion (309/399, 77.4%), and dryness (108/399, 27.1%). Ocular rosacea was confirmed in 149/309 cases who consulted an ophthalmologist (45.3%). A total of 159/399 (39.8%) had no pre-existing allergies. Eye involvement was significantly associated with the presence of skin symptoms (P < 0.05), impacting patients' general well-being and overall treatment satisfaction. About half of Demodex-positive patients (21/45, 46.7%) showed ocular symptoms.

Conclusions: Eye involvement in rosacea patients was common, often presenting with unspecific symptoms.

MeSH terms

  • Chalazion*
  • Eye
  • Germany / epidemiology
  • Humans
  • Rosacea* / complications
  • Rosacea* / diagnosis
  • Rosacea* / epidemiology