All-Cause Mortality Risk Prediction in Older Adults with Cancer: Practical Approaches and Limitations

Curr Oncol Rep. 2022 Nov;24(11):1377-1385. doi: 10.1007/s11912-022-01303-2. Epub 2022 Jun 1.

Abstract

Purpose of review: The prediction of all-cause mortality is an important component of shared decision-making across the cancer care continuum, particularly in older adults with limited life expectancy, for whom there is an increased risk of over-diagnosis and treatment.

Recent findings: Currently, several international societies recommend the use of all-cause mortality risk prediction tools when making decisions regarding screening and treatment in geriatric oncology. Here, we review some practical aspects of the utilization of those tools and dissect the characteristics of those most employed in geriatric oncology, highlighting both their advantages and their limitations.

Keywords: Cancer; Clinical decision rules; Decision-making; Life expectancy; Mortality; Older adults; Prognosis.

Publication types

  • Review

MeSH terms

  • Aged
  • Decision Making
  • Decision Making, Shared
  • Geriatric Assessment
  • Humans
  • Life Expectancy
  • Mass Screening
  • Neoplasms* / diagnosis
  • Neoplasms* / therapy