Identification of the novel HLA-DQB1*03:483 allele by sequencing-based typing

HLA. 2022 Oct;100(4):400-401. doi: 10.1111/tan.14699. Epub 2022 Jun 14.

Authors

Mohammed Alzahrani¹, Hanan Alanazi¹, Abdullah Alshubaili¹, Aisha Alanazi¹, Ali H Hajeer¹

Affiliation

¹ HLA Typing Lab, Department of Pathology and Laboratory Medicine, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.

PMID: 35657272
DOI: 10.1111/tan.14699

Abstract

A single nucleotide change in exon 1 of HLA-DQB1*03:01:01:03 results in the novel HLA-DQB1*03:483 allele.

Keywords: HLA-DQB1; Saudi Arabia; genomic sequence; new allele.

© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Review

MeSH terms

Alleles*
Base Sequence
HLA-DQ beta-Chains / genetics
Humans
Sequence Analysis, DNA / methods

Substances

HLA-DQ beta-Chains
HLA-DQB1 antigen