Vestibular neuronitis after COVID-19 vaccination

BMJ Case Rep. 2022 Jun 6;15(6):e247234. doi: 10.1136/bcr-2021-247234.

Abstract

A woman in her 50s presented with acute vertigo and vomiting within 72 hours of receiving the Pfizer-BioNTech COVID-19 vaccine. The only neurological deficit was an impaired vestibulo-ocular reflex with horizontal nystagmus. The patient was subsequently diagnosed with vestibular neuronitis. She was managed symptomatically with prochlorperazine and betahistine, and underwent vestibular rehabilitation for 6 weeks. She made a full recovery and experienced no further symptoms. She received the second dose of the vaccine without complications.This case demonstrates a temporal association between COVID-19 vaccination and vestibular neuronitis. Neurological adverse events are rare but recognised side effects of COVID-19 vaccines and healthcare professionals should be aware of them. This ensures timely management of patients with such presentations. Treatment should be the same as for non-vaccine-associated vestibular neuronitis. The nature of the relationship between COVID-19 vaccination and vestibular neuronitis remains unclear and patients therefore require investigations to exclude other recognised causes of vestibular neuronitis.

Keywords: COVID-19; Cranial nerves; Neurology (drugs and medicines); Public health; Unwanted effects / adverse reactions.

Publication types

  • Case Reports

MeSH terms

  • BNT162 Vaccine* / adverse effects
  • COVID-19* / prevention & control
  • Female
  • Humans
  • Vaccination / adverse effects
  • Vestibular Neuronitis* / chemically induced

Substances

  • BNT162 Vaccine