Molecular Biology in Glioblastoma Multiforme Treatment

Claudia Abbruzzese; Michele Persico; Silvia Matteoni; Marco G Paggi

doi:10.3390/cells11111850

Molecular Biology in Glioblastoma Multiforme Treatment

Cells. 2022 Jun 5;11(11):1850. doi: 10.3390/cells11111850.

Authors

Claudia Abbruzzese¹, Michele Persico², Silvia Matteoni¹, Marco G Paggi¹

Affiliations

¹ Cellular Networks and Molecular Therapeutic Targets, Proteomics Unit, IRCCS-Regina Elena National Cancer Institute, 00144 Rome, Italy.
² Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

Abstract

Glioblastoma (GBM, grade IV astrocytoma), the most frequently occurring primary brain tumor, presents unique challenges to therapy due to its location, aggressive biological behavior, and diffuse infiltrative growth, thus contributing to having disproportionately high morbidity and mortality [...].

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Astrocytoma* / pathology
Brain Neoplasms* / genetics
Brain Neoplasms* / therapy
Glioblastoma* / genetics
Glioblastoma* / therapy
Humans
Molecular Biology

Grants and funding

This work has been financed by Funds Ricerca Corrente 2022 from The Italian Ministry of Health to M.G.P.