Analysis of risk factors for a poor functional prognosis and relapse in patients with autoimmune encephalitis

J Neuroimmunol. 2022 Aug 15:369:577899. doi: 10.1016/j.jneuroim.2022.577899. Epub 2022 Jun 3.

Abstract

This retrospective study analyzed the clinical characteristics of autoimmune encephalitis (AE) patients to explore the predictors of poor prognosis. According to the modified Rankin scale score at the last follow-up, the functional prognosis of the patients was reflected. And the prognosis of the patients was comprehensively evaluated by the functional prognosis and the relapse of the patients. The results showed that disturbance of consciousness and delayed first-line immunotherapy were independent risk factors for the poor functional prognosis of AE. In addition, patients with psychiatric symptoms, should be alert for relapse.

Keywords: Autoimmune encephalitis; Clinical characteristics; Functional prognosis; Relapse.

MeSH terms

  • Encephalitis*
  • Hashimoto Disease
  • Humans
  • Prognosis
  • Recurrence
  • Retrospective Studies
  • Risk Factors

Supplementary concepts

  • Hashimoto's encephalitis