Concordance in psychopharmacological treatment before and after first mental health consultation

Arch Psychiatr Nurs. 2022 Aug:39:66-72. doi: 10.1016/j.apnu.2022.03.011. Epub 2022 Mar 25.

Abstract

Purpose: To analyse concordance between treatment prescribed before and after the first mental health consultation. We understand concordance in two different senses: first, as a similar amount of equivalent doses and drug type; second, as a similar treatment for each patient.

Method: This is an analytical, descriptive, retrospective study on psychopharmacological treatment before and after first mental health consultation of 1236 patients. Drugs were classified into four groups and the equivalent dose respect to reference medication was considered in each group in order to make a comparison between primary and mental health.

Results: Moderate concordance was found in prescribed treatments before and after first mental health consultation (except antidepressants). The average number of benzodiazepines decreased, as did average doses prescribed at mental health consultation respect to previously prescribed treatment; average doses of antidepressants, however, increased. From the patient's perspective, dose increase was more frequent than decrease. Nevertheless, a high percentage of polymedicated patients were found, although this percentage decreased after the first mental health consultation.

Conclusion: There exists a moderate concordance between the pharmacological treatment prescribed before and after the first mental health consultation. However, the use of benzodiazepines diminished significantly after the first consultation, mainly due to a decrease in the percentage of polymedicated patients.

Keywords: Concordance; Mental health; Polypharmacy; Psychopharmacology/therapy.

MeSH terms

  • Antidepressive Agents / therapeutic use
  • Benzodiazepines / therapeutic use
  • Humans
  • Mental Health*
  • Referral and Consultation*
  • Retrospective Studies

Substances

  • Antidepressive Agents
  • Benzodiazepines