Helicobacter pylori infection is an infectious disease and the empiric therapy paradigm should be changed

Hong Li; Tiankuo Yang; Hong Tang; Xiaoqiong Tang; Yalin Shen; Mohammed Benghezal; Alfred Tay; Barry Marshall

doi:10.1093/pcmedi/pbz009

Helicobacter pylori infection is an infectious disease and the empiric therapy paradigm should be changed

Precis Clin Med. 2019 Jun;2(2):77-80. doi: 10.1093/pcmedi/pbz009. Epub 2019 Jun 19.

Authors

Hong Li¹, Tiankuo Yang¹, Hong Tang¹, Xiaoqiong Tang¹, Yalin Shen¹, Mohammed Benghezal¹, Alfred Tay², Barry Marshall²

Affiliations

¹ West China Marshall Research Center for Infectious Diseases, Center of Infectious Diseases, Division of Infectious Diseases, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
² Helicobacter pylori Research Laboratory, School of Biomedical Sciences, Marshall Centre for Infectious Disease Research and Training, University of Western Australia, Nedlands, Australia.

Abstract

Helicobacter pylori infection is an infectious disease. Given the alarmingly high antibiotic resistance in H. pylori, gastroenterologists should change the empiric H. pylori treatment paradigm to an antimicrobial susceptibility testing-guided precision treatment. Antimicrobial stewardship programs for H. pylori should be implemented locally, regionally, and nationally to monitor the antibiotic resistance pattern.

Keywords: Helicobacter pylori; antimicrobial susceptibility testing; infectious disease.