17 beta-carboxamide steroids are a new class of glucocorticoid antagonists

Nature. 1979 May 10;279(5709):158-60. doi: 10.1038/279158a0.
No abstract available

MeSH terms

  • Animals
  • Cells, Cultured
  • Dexamethasone / analogs & derivatives*
  • Dexamethasone / metabolism
  • Dexamethasone / pharmacology
  • Enzyme Induction / drug effects
  • Glucocorticoids / antagonists & inhibitors*
  • Liver Neoplasms, Experimental / enzymology
  • Receptors, Glucocorticoid / metabolism
  • Structure-Activity Relationship
  • Tyrosine Transaminase / biosynthesis

Substances

  • Glucocorticoids
  • Receptors, Glucocorticoid
  • Dexamethasone
  • Tyrosine Transaminase