SARS-CoV-2-induced senescence as a potential therapeutic target

Mary Denholm; Robert C Rintoul; Daniel Muñoz-Espín

doi:10.1183/13993003.01101-2022

SARS-CoV-2-induced senescence as a potential therapeutic target

Eur Respir J. 2022 Aug 18;60(2):2201101. doi: 10.1183/13993003.01101-2022. Print 2022 Aug.

Authors

Mary Denholm^{1

2}, Robert C Rintoul^{3

4}, Daniel Muñoz-Espín^{5

4}

Affiliations

¹ Early Cancer Institute, Dept of Oncology, University of Cambridge, Cambridge, UK.
² Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
³ Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK.
⁴ Cancer Research UK Cambridge Centre Thoracic Cancer Programme, Cambridge, UK.
⁵ Early Cancer Institute, Dept of Oncology, University of Cambridge, Cambridge, UK [email protected].

Abstract

Long implicated in the pathology of ageing, cancer and many other systemic diseases, cellular senescence is now emerging as a key factor in the pathogenesis of severe COVID-19, with implications for other viral illnesses. https://bit.ly/3bbmOuT

Publication types

Editorial
Comment

MeSH terms

COVID-19*
Humans
Mutagenesis
Phenotype
Pneumonia*
SARS-CoV-2

Abstract

Publication types

MeSH terms

Grants and funding