Borane/Gold(I)-Catalyzed C-H Functionalization Reactions and Cycloaddition Reactions of Amines and α-Alkynylenones

Jun-Jie Tian; Wei Sun; Rui-Rui Li; Gui-Xiu Tian; Xiao-Chen Wang

doi:10.1002/anie.202208427

Borane/Gold(I)-Catalyzed C-H Functionalization Reactions and Cycloaddition Reactions of Amines and α-Alkynylenones

Angew Chem Int Ed Engl. 2022 Aug 26;61(35):e202208427. doi: 10.1002/anie.202208427. Epub 2022 Jul 20.

Authors

Jun-Jie Tian¹, Wei Sun¹, Rui-Rui Li¹, Gui-Xiu Tian¹, Xiao-Chen Wang¹

Affiliation

¹ State Key Laboratory and Institute of Elemento-Organic Chemistry, Haihe Laboratory of Sustainable Chemical Transformations, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, 94 Weijin Road, Tianjin, 300071, China.

PMID: 35785513
DOI: 10.1002/anie.202208427

Abstract

We designed a borane/gold(I) co-catalytic system and used it for C-H functionalization reactions and cycloaddition reactions between tertiary amines and α-alkynylenones. Both reactions effectively incorporated a furan ring into the amine.

Keywords: Boron; Cycloadditions; C−H Functionalization; Gold; Homogeneous Catalysis.

Abstract

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