Inactivated Poliovirus Vaccine Closing the Type 2 Immunity Gap in Vietnam

Dang Thi Thanh Huyen; Dang Duc Anh; Nguyen Thanh Trung; Duong Thi Hong; Tran Trung Thanh; Luong Ngoc Truong; Visalakshi Jeyaseelan; Rocio Lopez Cavestany; William S Hendley; Bernardo A Mainou; Ondrej Mach

doi:10.1093/jpids/piac046

Inactivated Poliovirus Vaccine Closing the Type 2 Immunity Gap in Vietnam

J Pediatric Infect Dis Soc. 2022 Sep 29;11(9):413-416. doi: 10.1093/jpids/piac046.

Affiliations

¹ Expanded Program on Immunizations Department, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
² Thanh Hoa Provincial CDC, Thanh Hoa, Vietnam.
³ Polio Eradication Department, World Health Organization, Geneva, Switzerland.
⁴ CNA, Contracting Agency to the Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
⁵ Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Abstract

This was a cross-sectional community-based serological survey of polio antibodies assessing the immunogenicity of inactivated poliovirus vaccine (IPV) focusing on poliovirus serotype 2. IPV was administered to 5-month-old children. Type 2 antibody seroprevalence when measured 1 month after IPV administration was >95%. One IPV dose successfully closed the immunity gap.

Keywords: Vietnam; inactivated poliovirus vaccine; polio eradication; poliomyelitis; routine immunization.

MeSH terms

Antibodies, Viral
Child
Cross-Sectional Studies
Humans
Immunization Schedule
Infant
Poliomyelitis* / prevention & control
Poliovirus Vaccine, Inactivated
Poliovirus*
Seroepidemiologic Studies
Vietnam / epidemiology

Substances

Antibodies, Viral
Poliovirus Vaccine, Inactivated

Grants and funding

001/WHO_/World Health Organization/International