Metastatic primary gastric melanoma: a rare clinical presentation and a review of literature

Bikash Ranjan Mahapatra; Anupam Muraleedharan; Saroj Kumar Das Majumdar; Amit Kumar Adhya

doi:10.1136/bcr-2022-249312

Metastatic primary gastric melanoma: a rare clinical presentation and a review of literature

BMJ Case Rep. 2022 Jul 14;15(7):e249312. doi: 10.1136/bcr-2022-249312.

Authors

Bikash Ranjan Mahapatra¹, Anupam Muraleedharan¹, Saroj Kumar Das Majumdar², Amit Kumar Adhya³

Affiliations

¹ Department of Radiotherapy, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
² Department of Radiotherapy, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India [email protected].
³ Department of Pathology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Abstract

Primary gastric melanoma is a rare clinical finding. It presents with upper gastrointestinal symptoms like abdominal pain, weight loss and melaena. It is often difficult to differentiate a primary gastric melanoma from primary cutaneous melanoma with gastric metastasis. Upper gastrointestinal endoscopy and biopsy of the lesion for histopathology and immunohistochemistry help to reach a definite diagnosis. We report a case of primary gastric melanoma with metastases to the liver and bone. The patient was treated with palliative radiotherapy, palliative chemotherapy and a bone-stabilising agent.

Keywords: Cancer intervention; Gastric cancer; Malignant disease and immunosuppression; Pathology; Radiotherapy.

Publication types

Case Reports

MeSH terms

Biopsy
Humans
Melanoma* / diagnosis
Melanoma* / pathology
Melanoma* / therapy
Neoplasms, Second Primary*
Skin Neoplasms* / diagnosis
Skin Neoplasms* / pathology
Stomach Neoplasms* / diagnosis
Stomach Neoplasms* / pathology
Stomach Neoplasms* / therapy