Subgroup-specific roles of primary cilia in medulloblastoma

Genes Dev. 2022 Jun 1;36(11-12):650-651. doi: 10.1101/gad.349856.122.

Abstract

Here I discuss the study in this issue of Genes & Development by Youn et al. (pp. 737-751), which describes defined and diverse roles of primary cilia in molecularly distinct medulloblastoma subgroups, highlighting once again the importance of designing subgroup-specific therapeutic approaches for this tumor.

Keywords: WNT; cell cycle; cilia; medulloblastoma; translation.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cerebellar Neoplasms* / genetics
  • Cilia / genetics
  • Humans
  • Medulloblastoma* / genetics