Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates

Yi Wu; Yanqiong Shen; Namei Wu; Xinghai Zhang; Shaohong Chen; Chang Yang; Junhui Zhou; Yan Wu; Da Chen; Li Wang; Chao Wang; Huajun Zhang; Ninuo Xia; Sandra Chiu; Yucai Wang

doi:10.1038/s41422-022-00706-x

Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates

Cell Res. 2022 Oct;32(10):949-952. doi: 10.1038/s41422-022-00706-x. Epub 2022 Aug 1.

Authors

Yi Wu^#^{1

2}, Yanqiong Shen^#², Namei Wu^#^{1

2}, Xinghai Zhang^#³, Shaohong Chen^{3

4}, Chang Yang^{1

2}, Junhui Zhou^{3

4}, Yan Wu³, Da Chen⁵, Li Wang², Chao Wang⁵, Huajun Zhang⁶, Ninuo Xia⁷, Sandra Chiu⁸, Yucai Wang^{9

10

11}

Affiliations

¹ Department of Radiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
² School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
³ State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China.
⁴ University of Chinese Academy of Sciences, Beijing, China.
⁵ MOE Key Laboratory for Cellular Dynamics, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
⁶ State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China. [email protected].
⁷ School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China. [email protected].
⁸ School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China. [email protected].
⁹ Department of Radiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China. [email protected].
¹⁰ School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China. [email protected].
¹¹ RNAlfa Biotech, Hefei, Anhui, China. [email protected].

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antibodies, Neutralizing*
Antibodies, Viral
Cricetinae
Immunity
Mice
Primates
Vaccines, Synthetic*
mRNA Vaccines

Substances

Antibodies, Neutralizing
Antibodies, Viral
Vaccines, Synthetic
mRNA Vaccines