A novel HLA-DQA101 allele, HLA-DQA101:99, identified by next-generation sequencing

HLA. 2022 Dec;100(6):662-664. doi: 10.1111/tan.14758. Epub 2022 Aug 15.

Authors

Manli Shen¹, Brian F Duffy², Jo-Ellen Jennemann², Bijal A Parikh¹, Chang Liu¹

Affiliations

¹ Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, Missouri, USA.
² Department of Laboratories, Barnes-Jewish Hospital, St. Louis, Missouri, USA.

PMID: 35933577
DOI: 10.1111/tan.14758

Abstract

DQA1*01:99 differs from DQA1*01:01 by a missense nucleotide substitution in exon 4.

Keywords: DQA1*01:99; HLA novel alleles; next-generation sequencing.

© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
HLA-DQ alpha-Chains / genetics
High-Throughput Nucleotide Sequencing*
Humans
Sequence Analysis, DNA

Substances

HLA-DQA1 antigen
HLA-DQ alpha-Chains