Cutaneous dirt-adherent disease complicated with Darier's disease, schizophrenia, and cutis verticis gyrata: A case report

Qing Zhu; Shu-Jing Guo; Bin Wang; Lu-Lu Xu; Guo-Qiang Zhang

doi:10.3389/fmed.2022.939107

Cutaneous dirt-adherent disease complicated with Darier's disease, schizophrenia, and cutis verticis gyrata: A case report

Front Med (Lausanne). 2022 Jul 29:9:939107. doi: 10.3389/fmed.2022.939107. eCollection 2022.

Authors

Qing Zhu¹, Shu-Jing Guo¹, Bin Wang¹, Lu-Lu Xu¹, Guo-Qiang Zhang¹

Affiliation

¹ Department of Dermatology, The First Affiliated Hospital of Hebei Medical University, Shijiazhuang, China.

Abstract

The patient was a 25-year-old man presented with cutaneous dirt-adherent disease with a past medical history of schizophrenia. Both the patient and his mother had Darier's disease, genetic screening revealed that the patient carried a heterozygous frameshift mutation in ATP2A2 gene, which was inherited from his mother. Cutis verticis gyrata was also found in the patient.

Keywords: ATP2A2 gene; cutaneous dirt-adherent; gyrate cranial skin; keratosis follicularis; schizophrenia.

Publication types

Case Reports