Rates of complication for dilation and evacuation versus induction of labor in treatment of second trimester intrauterine fetal demise

Eur J Obstet Gynecol Reprod Biol. 2022 Oct:277:16-20. doi: 10.1016/j.ejogrb.2022.08.003. Epub 2022 Aug 9.

Abstract

Objective: To evaluate clinical differences in the safety of dilation and evacuation (D&E) and induction of labor (IOL) for the treatment of intrauterine fetal demise (IUFD) between 14 and 24 weeks gestation.

Study designs: A retrospective chart review was conducted at a single institution comparing rates of major and minor complications between patients who undergo D&E and those that undergo IOL in the treatment of IUFD between 14 and 24 weeks gestation. Demographic and medical variables were stratified by management method and analyzed using chi-squared and t-tests where appropriate.

Results: Patients who underwent IOL were of a more advanced gestational age and more likely to be uninsured. Patients who underwent D&E were more likely to be privately insured. Hospital time for an IOL was significantly longer than for D&E. Composite rates of complication did not differ significantly between management groups. Patients treated with D&E were more likely to require uterine aspiration.

Conclusions: D&E and IOL are equally safe methods for the management of IUFD between 14 and 24 weeks gestation. Both options should be made available to patients who experience this rare pregnancy outcome.

Keywords: Dilation and evacuation; Induction of labor; Intrauterine fetal demise; Mid-trimester loss.

MeSH terms

  • Abortion, Induced* / adverse effects
  • Abortion, Induced* / methods
  • Dilatation
  • Female
  • Fetal Death* / etiology
  • Humans
  • Labor, Induced / adverse effects
  • Labor, Induced / methods
  • Pregnancy
  • Pregnancy Trimester, Second
  • Retrospective Studies
  • Stillbirth