We demonstrate that 6 distinct Peromyscus rodent species are permissive to experimental infection with Sin Nombre orthohantavirus (SNV). Viral RNA and SNV antibodies were detected in members of all 6 species. P. leucopus mice demonstrated markedly higher viral and antibody titers than P. maniculatus mice, the established primary hosts for SNV.
Keywords: Orthohantaviruses; Peromyscus; Peromyscus leucopus; Peromyscus maniculatus; Sin Nombre virus; hantavirus cardiopulmonary syndrome; rodents; viruses.