A CRISPR/Cas9 engineered MplS504N mouse model recapitulates human myelofibrosis

Leukemia. 2022 Oct;36(10):2535-2538. doi: 10.1038/s41375-022-01684-0. Epub 2022 Aug 23.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • CRISPR-Cas Systems
  • Disease Models, Animal
  • Humans
  • Mice
  • Primary Myelofibrosis* / genetics
  • Receptors, Thrombopoietin / genetics

Substances

  • Receptors, Thrombopoietin
  • MPL protein, human