Pulmonary Embolism Presenting with Pulmonary Infarction: Update and Practical Review of Literature Data

J Clin Med. 2022 Aug 21;11(16):4916. doi: 10.3390/jcm11164916.

Abstract

Pulmonary infarction (PI) is a possible consequence of pulmonary embolism (PE). The real incidence of PI could be underestimated considering only non-fatal PE presentation. However, following postmortem examination, the prevalence of PI is considerably higher. This evidence suggests the necessity of proper diagnostic protocol for identifying PI. Unfortunately, PI diagnosis can sometimes be challenging, due to the overlapping of symptoms with other diseases. Nowadays, the diagnosis is mainly based on radiological evaluation, although the combination with emerging imaging techniques such as ultrasound and nuclear scanning might improve the diagnostic algorithm for PI. This review aims to summarize the available data on the prevalence of PI, the main predisposing factors for the development of PI among patients with PE, to resume the possible diagnostic tools, and finally the clinical and prognostic implications.

Keywords: diagnostic algorithm; pulmonary embolism; pulmonary infarction; pulmonary ultrasound.

Publication types

  • Review

Grants and funding

This work was supported by Regione Friuli Venezia Giulia (grant for the project “Morti cardiache improvvise in età giovanile”) according to the regional low LR 26/2020.