Prevalence of Protein-Energy Wasting in Dialysis Patients Using a Practical Online Tool to Compare with Other Nutritional Scores: Results of the Nutrendial Study

Nutrients. 2022 Aug 17;14(16):3375. doi: 10.3390/nu14163375.

Abstract

This cross-sectional study aims to explore the prevalence of protein-energy wasting (PEW) in dialysis patients in Catalonia, Spain, using a new and practical online tool which enables rapid calculation and comparison with other nutritional scores.

Methods: A web tool (Nutrendial) was created to introduce different variables and automatically calculate PEW, Malnutrition inflammation Score (MIS) and Subjective Global Assessment (SGA) in 1389 patients (88% in haemodialysis (HD)), 12% in peritoneal dialysis (PD) from different regions of Catalonia.

Results: A prevalence of 23.3% (26% HD, 10.2% PD) of PEW was found, with a mean MIS score of 6 and SGA score of C in 7% of the patients. ROC analysis showed MIS as the best nutritional score to diagnose PEW (AUC 0.85). Albumin delivered lower diagnostic precision (AUC 0.77) and sensitivity (66%). A cut off point of 7 (86% sensitivity and 75% specificity) for MIS and 3.7 mg/dL for albumin were found to predict the appearance of PEW in this population. SGA B or C showed an 87% sensitivity and 55% specificity to diagnose PEW. Very low nutritional intervention (14%) was recorded with this tool in patients with PEW.

Conclusions: This new online tool facilitated the calculation of PEW, enabling different professionals-including nephrologists, dieticians and nurses-to efficiently obtain insights into the nutritional status of the Catalonian dialysis population and implement the required nutritional interventions. MIS is the score with more sensitivity to diagnose PEW.

Keywords: dialysis; malnutrition inflammation score; nutritional assessment; online tool; protein-energy wasting; subjective global assessment.

Publication types

  • Comparative Study

MeSH terms

  • Albumins
  • Cachexia*
  • Cross-Sectional Studies
  • Humans
  • Inflammation / diagnosis
  • Kidney Failure, Chronic / therapy
  • Nutritional Status
  • Prevalence
  • Protein-Energy Malnutrition* / diagnosis
  • Protein-Energy Malnutrition* / epidemiology
  • Protein-Energy Malnutrition* / etiology
  • Renal Dialysis* / adverse effects

Substances

  • Albumins

Grants and funding

This research received no external funding.