Current Trends of Computational Tools in Geriatric Medicine and Frailty Management

Anna Maria Louka; Christos Tsagkaris; Panagiotis Christoforou; Andleeb Khan; Filia Alexiou; Panagiota Simou; Ioannis Haranas; Ioannis Gkigkitzis; Georgios Zouganelis; Niraj Kumar Jha; Md Sahab Uddin; Bairong Shen; Mohammad A Kamal; Ghulam Md Ashraf; Athanasios Alexiou

doi:10.31083/j.fbl2708232

Current Trends of Computational Tools in Geriatric Medicine and Frailty Management

Front Biosci (Landmark Ed). 2022 Jul 29;27(8):232. doi: 10.31083/j.fbl2708232.

Authors

Anna Maria Louka^{1

2}, Christos Tsagkaris^{2

3}, Panagiotis Christoforou⁴, Andleeb Khan⁵, Filia Alexiou^{6

7}, Panagiota Simou⁶, Ioannis Haranas⁸, Ioannis Gkigkitzis⁹, Georgios Zouganelis¹⁰, Niraj Kumar Jha^{11

12}, Md Sahab Uddin^{13

14}, Bairong Shen¹⁵, Mohammad A Kamal^{15

16

17

18}, Ghulam Md Ashraf^{19

20}, Athanasios Alexiou^{21

22}

Affiliations

¹ Faculty of Medicine, University of Thessaly, 41500 Larissa, Greece.
² Novel Global Community Educational Foundation, NSW 2770 Hebersham, Australia.
³ Faculty of Medicine, University of Crete, 28403 Heraklion, Greece.
⁴ Department of Pathophysiology, Medical School, National University of Athens, 11527 Athens, Greece.
⁵ Department of Pharmacology & Toxicology, College of Pharmacy, Jazan University, 45142 Jazan, Saudi Arabia.
⁶ Department of Social Studies and Arts, Novel Global Community Educational Foundation, NSW 2770 Hebersham, Australia.
⁷ Department of Business Administration, University of West Attica, 12243 Athens, Greece.
⁸ Department of Physics and Computer Science, Wilfrid Laurier University, Waterloo, ON N2L-3C5, Canada.
⁹ Department of Mathematics, Northern Virginia Community College, 21200 Campus Drive, Sterling, VA 20164-8699, USA.
¹⁰ School of Human Sciences, College of Life and Natural Sciences, University of Derby, DE22 1GB Derby, UK.
¹¹ Department of Biotechnology, School of Engineering & Technology (SET), Sharda University, 201310 Greater Noida, Uttar Pradesh, India.
¹² Department of Biotechnology, School of Applied & Life Sciences (SALS), Uttaranchal University, 248007 Dehradun, India.
¹³ Department of Pharmacy, Southeast University, 1213 Dhaka, Bangladesh.
¹⁴ Pharmakon Neuroscience Research Network, 1341 Dhaka, Bangladesh.
¹⁵ West China School of Nursing/Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, 610041 Chengdu, Sichuan, China.
¹⁶ King Fahd Medical Research Center, King Abdulaziz University, 21589 Jeddah, Saudi Arabia.
¹⁷ Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, 1341 Dhaka, Bangladesh.
¹⁸ Enzymoics, Peterlee Place, NSW 2770 Hebersham, Australia.
¹⁹ Pre-Clinical Research Unit, King Fahd Medical Research Center, King Abdulaziz University, 22254 Jeddah, Saudi Arabia.
²⁰ Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, 22254 Jeddah, Saudi Arabia.
²¹ Department of Science and Engineering, Novel Global Community Educational Foundation, NSW 2770 Hebersham, Australia.
²² AFNP Med Austria, 1030 Wien, Austria.

PMID: 36042184
DOI: 10.31083/j.fbl2708232

Abstract

While frailty corresponds to a multisystem failure, geriatric assessment can recognize multiple pathophysiological lesions and age changes. Up to now, a few frailty indexes have been introduced, presenting definitions of psychological problems, dysregulations in nutritional intake, behavioral abnormalities, and daily functions, genetic, environmental, and cardiovascular comorbidities. The geriatric evaluation includes a vast range of health professionals; therefore, we describe a broad range of applications and frailty scales-biomarkers to investigate and formulate the relationship between frailty lesions, diagnosis, monitoring, and treatment. Additionally, artificial intelligence applications and computational tools are presented, targeting a more efficacy individualized geriatric management of healthy aging.

Keywords: aging; artificial intelligence; bioinformatics; brain-computer interface; dementia; expert systems; frailty; geriatrics.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Artificial Intelligence
Frail Elderly
Frailty* / diagnosis
Geriatric Assessment
Geriatrics*
Humans