Possible prenatal hydantoin effect in a child born to a nonepileptic mother

Am J Med Genet. 1987 Jun;27(2):373-8. doi: 10.1002/ajmg.1320270215.

Abstract

We describe a child who was born with marked digital hypoplasia of his right hand. Although the mother was not an epileptic, the child was exposed in utero to diphenylhydantoin.

MeSH terms

  • Abnormalities, Drug-Induced / etiology*
  • Adult
  • Arteriovenous Malformations / complications
  • Arteriovenous Malformations / surgery
  • Cerebral Hemorrhage / complications
  • Dermatoglyphics
  • Female
  • Fingers / abnormalities*
  • Humans
  • Infant, Newborn
  • Male
  • Maternal-Fetal Exchange
  • Phenytoin / adverse effects*
  • Phenytoin / therapeutic use
  • Pregnancy
  • Pregnancy Complications / drug therapy
  • Seizures / prevention & control

Substances

  • Phenytoin