[COPD and eosinophils]

Rev Mal Respir. 2022 Oct;39(8):685-697. doi: 10.1016/j.rmr.2022.08.005. Epub 2022 Aug 30.
[Article in French]

Abstract

COPD is a major cause of morbidity and mortality worldwide. As research progresses, new patient phenotypes are being defined, providing hope for more personalized management of the disease. A significant proportion of patients present with an increased level of blood eosinophils, which may reflect bronchial eosinophilic inflammation. The aims of this article are to characterize the role of eosinophils in COPD in terms of pathophysiology, associated respiratory symptoms, impact on treatment and, finally, to consider different future treatment options.

Keywords: BPCO; COPD; Eosinophils; Éosinophiles.

Publication types

  • Review

MeSH terms

  • Eosinophilia* / diagnosis
  • Eosinophilia* / etiology
  • Eosinophils
  • Humans
  • Pulmonary Disease, Chronic Obstructive* / diagnosis
  • Sputum