Vitiligo-like manifestations of graft-versus-host disease in a pediatric population

Julia Dai; Robert S Hight; Karina Grullon; Teresa L Xiao; Sarah L Stein

doi:10.1111/pde.15121

Vitiligo-like manifestations of graft-versus-host disease in a pediatric population

Pediatr Dermatol. 2023 Jan;40(1):157-161. doi: 10.1111/pde.15121. Epub 2022 Sep 5.

Authors

Julia Dai¹, Robert S Hight², Karina Grullon², Teresa L Xiao², Sarah L Stein^{3

4}

Affiliations

¹ Department of Dermatology, Division of Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
² University of Chicago Pritzker School of Medicine, Chicago, Illinois, USA.
³ Section of Dermatology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois, USA.
⁴ Department of Pediatrics, University of Chicago Medical Center, Chicago, Illinois, USA.

PMID: 36063124
DOI: 10.1111/pde.15121

Abstract

Vitiligo-like changes are an uncommon cutaneous manifestation of graft-versus-host disease (GVHD). We report three cases and review the literature of pediatric patients with vitiligo-like changes associated with GVHD. Improved characterization of this phenomenon may lend insight into the biologic pathways that underlie both vitiligo and GVHD.

Keywords: depigmentation; graft-versus-host disease; hypopigmentation; leukoderma; vitiligo.

Publication types

Case Reports

MeSH terms

Child
Graft vs Host Disease* / complications
Graft vs Host Disease* / diagnosis
Humans
Hypopigmentation*
Vitiligo* / etiology