Gain-of-Function Variants in Lipid Genes Enhance Biological Insight and Point Toward Therapeutic Opportunities

Circulation. 2022 Sep 6;146(10):740-742. doi: 10.1161/CIRCULATIONAHA.122.061233. Epub 2022 Sep 6.
No abstract available

Keywords: Editorials; LIPC protein, human; cholesterol, HDL; cholesterol, LDL; dyslipidemias; gain-of-function mutation; phospholipases.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Cholesterol, HDL
  • Cholesterol, LDL
  • Dyslipidemias* / drug therapy
  • Gain of Function Mutation*
  • Humans
  • Triglycerides

Substances

  • Cholesterol, HDL
  • Cholesterol, LDL
  • Triglycerides