Clinical utility of skin perfusion pressure measurement in diabetic foot wounds: An observational study

Medicine (Baltimore). 2022 Sep 9;101(36):e30454. doi: 10.1097/MD.0000000000030454.

Abstract

The degree of blood vessel stenosis significantly influences diabetic foot treatment. This study aimed to investigate the association between computed tomography angiography (CTA) stenosis and skin perfusion pressure (SPP), which are noninvasive vascular assessments used to evaluate diabetic foot wounds. Forty patients who reported diabetic foot wounds between November 2016 and December 2017 were included in the study. SPPand CTA were performed to evaluate the blood flow, and the rate of decrease in wound size was measured for the wounds corresponding to Meggitt-Wagner grade 1 at the first evaluation and 4-week intervals. The P value of the association between the degree of CTA stenosis and the SPP value was 0.915, and the P value of the association between CTA stenosis and decreasing rate of wound size was .235. There was no statistically significant association between SPP and the decreasing rate of wound size according to the degree of CTA stenosis. The association between SPP value and the decreasing rate of wound size was statistically significant (P < .05). The decreasing rate in diabetic foot wound size was significantly associated with SPP but not with CTA stenosis.

Publication types

  • Observational Study

MeSH terms

  • Computed Tomography Angiography
  • Constriction, Pathologic
  • Diabetes Mellitus*
  • Diabetic Foot* / therapy
  • Humans
  • Perfusion
  • Skin / diagnostic imaging