Successful treatment of acute respiratory distress syndrome caused by hypervirulent Klebsiella pneumoniae with extracorporeal membrane oxygenation and continuous renal replacement therapy: A case report and literature review

Wenzhong Peng; Yanhao Wu; Rongli Lu; Yunpeng Zheng; Jie Chen; Pinhua Pan

doi:10.3389/fmed.2022.936927

Successful treatment of acute respiratory distress syndrome caused by hypervirulent Klebsiella pneumoniae with extracorporeal membrane oxygenation and continuous renal replacement therapy: A case report and literature review

Front Med (Lausanne). 2022 Aug 24:9:936927. doi: 10.3389/fmed.2022.936927. eCollection 2022.

Authors

Wenzhong Peng^{1

2

3

4

5}, Yanhao Wu^{1

2

3

4

5}, Rongli Lu^{1

2

3

4

5}, Yunpeng Zheng^{1

2

3

4

5}, Jie Chen^{1

2

3

4

5}, Pinhua Pan^{1

2

3

4

5}

Affiliations

¹ Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China.
² Center of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China.
³ Clinical Research Center for Respiratory Diseases in Hunan Province, Xiangya Hospital, Central South University, Changsha, China.
⁴ Hunan Engineering Research Center for Intelligent Diagnosis and Treatment of Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China.
⁵ National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.

Abstract

Hypervirulent Klebsiella pneumoniae (hvKP) causes invasive infections and leads to high morbidity and mortality rates. Here, we report the case of a Chinese man with diabetes mellitus who developed acute respiratory distress syndrome and septic shock due to hvKP belonging to the K1 strain. The patient was treated with venovenous extracorporeal membrane oxygenation and continuous renal replacement therapy, in combination with antibiotics and recovered well. Clinicians should be aware of fatal infections caused by hvKP and investigate the best treatment options for patients at various stages of infection.

Keywords: acute respiratory distress syndrome (ARDS); continuous renal replacement therapy (CRRT); extracorporeal membrane oxygenation (ECMO); hypervirulent Klebsiella pneumoniae (hvKP); septic shock.

Publication types

Case Reports