What Is the Best Treatment for Acute Limb Ischemia?

Elizabeth G King; Alik Farber

doi:10.1016/j.yasu.2022.03.004

What Is the Best Treatment for Acute Limb Ischemia?

Adv Surg. 2022 Sep;56(1):287-304. doi: 10.1016/j.yasu.2022.03.004.

Authors

Elizabeth G King¹, Alik Farber²

Affiliations

¹ Division of Vascular & Endovascular Surgery, Boston University School of Medicine 85 East Concord Street, Suite 3000, Boston, MA 02118, USA.
² Division of Vascular & Endovascular Surgery, Boston University School of Medicine 85 East Concord Street, Suite 3000, Boston, MA 02118, USA. Electronic address: [email protected].

PMID: 36096573
DOI: 10.1016/j.yasu.2022.03.004

Abstract

Acute limb ischemia (ALI) is a vascular emergency associated with high rates of limb loss and mortality. Management of these patients is challenging given the severe systemic illness resulting from tissue ischemia and the high incidence of preexisting comorbid conditions and underlying peripheral arterial disease. Expeditious diagnosis, anticoagulation, and revascularization are of utmost importance in reducing morbidity. Revascularization may be accomplished using open, endovascular, or hybrid techniques. Approach to revascularization depends on the severity of ischemia, location of occlusion, cause, chance of recovery, comorbidities, and available resources.

Keywords: Acute limb ischemia (ALI); Catheter-directed thrombolysis; Embolectomy; Pharmacomechanical thrombectomy.

Publication types

Review

MeSH terms

Arterial Occlusive Diseases*
Humans
Ischemia / diagnosis
Ischemia / etiology
Ischemia / surgery
Peripheral Arterial Disease* / diagnosis
Peripheral Arterial Disease* / surgery
Risk Factors
Treatment Outcome