Case of recurrent superficial CD34-positive fibroblastic tumor

J Cutan Pathol. 2023 Jun;50(6):477-480. doi: 10.1111/cup.14329. Epub 2022 Nov 4.

Abstract

Superficial CD34-positive fibroblastic tumor (SCPFT) is a recently described rare superficial mesenchymal tumor. SCPFT has a distinctive morphologic appearance, marked by significant nuclear pleomorphism, low mitotic rate, and diffuse CD34 positivity. SCPFT is underdiagnosed because of its rarity and misdiagnosis as sarcoma, with very few reported cases of local recurrence or metastasis. Recognition and awareness of SCPFT are essential for accurate diagnosis and appropriate clinical management. We describe here the case of a 37-year-old male who presented with a right calf mass diagnosed as SCPFT with subsequent local recurrence of the tumor.

Keywords: CD34 positive; SCPFT; fibroblastic tumor; recurrence.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antigens, CD34
  • Biomarkers, Tumor
  • Humans
  • Immunohistochemistry
  • Male
  • Neoplasms, Fibrous Tissue* / diagnosis
  • Neoplasms, Fibrous Tissue* / pathology
  • Soft Tissue Neoplasms* / pathology

Substances

  • Biomarkers, Tumor
  • Antigens, CD34