Point-of-care testing allows successful simultaneous screening of sickle cell disease, HIV, and tuberculosis for households in rural Guinea-Bissau, West Africa

Pediatr Blood Cancer. 2022 Dec;69(12):e30009. doi: 10.1002/pbc.30009. Epub 2022 Sep 25.

Abstract

Diagnosis of noncommunicable genetic diseases like sickle cell disease (SCD) and communicable diseases such as human immunodeficiency virus (HIV) or tuberculosis (TB) is often difficult in rural areas of Africa due to the lack of infrastructures, trained staff, or capacity to involve families living in remote areas. The availability of point-of-care (POC) tests for the above diseases offers the opportunity to build joint programs to tackle all conditions. We report successful simultaneous screening of SCD, HIV, and TB utilizing POC tests in 898 subjects in Fanhe, in rural Guinea-Bissau. Adherence was 100% and all diagnosed subjects were enrolled in care programs.

Keywords: Guinea-Bissau; HIV; point of care; sickle cell disease; tuberculosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Africa, Western
  • Anemia, Sickle Cell* / diagnosis
  • Guinea-Bissau / epidemiology
  • HIV Infections* / complications
  • HIV Infections* / diagnosis
  • HIV Infections* / epidemiology
  • Humans
  • Point-of-Care Testing
  • Tuberculosis* / diagnosis
  • Tuberculosis* / epidemiology