[Castleman disease]

Ann Pathol. 2023 Jan;43(1):13-24. doi: 10.1016/j.annpat.2022.07.013. Epub 2022 Sep 30.
[Article in French]

Abstract

The term "Castleman disease" covers a variety of entities that have very different clinical, biological, pathological and physiopathological features. In this issue, we review the characteristics of the unicentric Castleman disease, of the HHV8 associated multicentric Castleman disease and the idiopathic multicentric Castleman disease associated or not with TAFRO syndrome ("thrombocytopenia, anasarca, fever, reticulin myelofibrosis and/or renal insufficiency, organomegaly"). We detail the differential diagnostics of these entities.

Keywords: Castleman disease; HHV8; Maladie de Castleman; Multicentric; Multicentrique; Uncentric; Unicentrique.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Castleman Disease* / diagnosis
  • Castleman Disease* / pathology
  • Edema / pathology
  • Humans
  • Renal Insufficiency*
  • Thrombocytopenia* / complications
  • Thrombocytopenia* / pathology

Supplementary concepts

  • Multi-centric Castleman's Disease