Association between multimorbidity, intensive care unit admission, and death in patients with COVID-19 in Brazil: a cross-section study, 2020

Sao Paulo Med J. 2022 Oct 3;141(3):e2022226. doi: 10.1590/1516-3180.2022.0226.R1.21072022. eCollection 2022.

Abstract

Background: Multimorbidity can influence intensive care unit (ICU) admissions and deaths due to coronavirus disease (COVID-19).

Objective: To analyze the association between multimorbidity, ICU admissions, and deaths due to COVID-19 in Brazil.

Design and setting: This cross-sectional study was conducted using data from patients with severe acute respiratory syndrome (SARS) due to COVID-19 recorded in the Influenza Epidemiological Surveillance Information System (SIVEP-Gripe) in 2020.

Methods: Descriptive and stratified analyses of multimorbidity were performed based on sociodemographic, ventilatory support, and diagnostic variables. Poisson regression was used to estimate the prevalence ratios.

Results: We identified 671,593 cases of SARS caused by COVID-19, of which 62.4% had at least one morbidity. Multimorbidity was associated with male sex, age 60-70 and ≥ 80 years, brown and black skin color, elementary education and high school, ventilatory support, and altered radiologic exams. Moreover, all regions of the country and altered computed tomography due to COVID-19 or other diseases were associated with death; only the northeast region and higher education were associated with ICU admission.

Conclusion: Our results showed an association between multimorbidity, ICU admission, and death in COVID-19 patients in Brazil.

MeSH terms

  • Aged
  • Brazil / epidemiology
  • COVID-19*
  • Cross-Sectional Studies
  • Humans
  • Intensive Care Units
  • Male
  • Middle Aged
  • Multimorbidity
  • SARS-CoV-2