Research progress of risk factors and early diagnostic biomarkers of gout-induced renal injury

Front Immunol. 2022 Sep 20:13:908517. doi: 10.3389/fimmu.2022.908517. eCollection 2022.

Abstract

Gout renal injury has an insidious onset, no obvious symptoms, and laboratory abnormalities in the early stages of the disease. The injury is not easily detected, and in many cases, the patients have entered the renal failure stage at the time of diagnosis. Therefore, the detection of gout renal injury-related risk factors and early diagnostic biomarkers of gout renal injury is essential for the prevention and early diagnosis of the disease. This article reviews the research progress in risk factors and early diagnostic biomarkers of gout renal injury.

Keywords: biomarkers; early diagnosis; gout; gouty nephropathy; risk factors.

Publication types

  • Review

MeSH terms

  • Biomarkers
  • Gout Suppressants
  • Gout* / diagnosis
  • Gout* / drug therapy
  • Humans
  • Kidney
  • Risk Factors

Substances

  • Biomarkers
  • Gout Suppressants