Exploring vast microbial epitope spaces

Marc Marius Geissler; Sebastian Zeissig

doi:10.1016/j.immuni.2022.09.010

Exploring vast microbial epitope spaces

Immunity. 2022 Oct 11;55(10):1758-1760. doi: 10.1016/j.immuni.2022.09.010.

Authors

Marc Marius Geissler¹, Sebastian Zeissig²

Affiliations

¹ Center for Regenerative Therapies, Technische Universität (TU) Dresden, 01307 Dresden, Germany; Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, 01307 Dresden, Germany.
² Center for Regenerative Therapies, Technische Universität (TU) Dresden, 01307 Dresden, Germany; Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, 01307 Dresden, Germany. Electronic address: [email protected].

PMID: 36223724
DOI: 10.1016/j.immuni.2022.09.010

Abstract

The spectrum and origin of commensal bacterial HLA epitopes is not well understood. In this issue of Immunity, Pedersen et al. provide a systematic analysis of commensal bacterial HLA II epitopes and demonstrate plasticity of corresponding CD4⁺ T cell responses.

Publication types

Comment

MeSH terms

CD4-Positive T-Lymphocytes*
Epitopes, T-Lymphocyte*

Substances

Epitopes, T-Lymphocyte