Risk Assessment of Nitrite and Nitrate Intake from Processed Meat Products: Results from the Hellenic National Nutrition and Health Survey (HNNHS)

Int J Environ Res Public Health. 2022 Oct 6;19(19):12800. doi: 10.3390/ijerph191912800.

Abstract

Long-term exposure to a high nitrite and nitrate intake through processed meat is of concern, as it has been related to adverse health effects. Individual consumption data from 2152 participants (46.7% males) in the Hellenic National Nutrition and Health Survey (HNNHS) were linked with current Maximum Permitted Levels (MPLs) to calculate exposure to nitrite and nitrate from processed meat products (assessed as nitrite equivalent), evaluate potential risk and identify the major contributors. Processed meat intakes were determined by combining data from 24 h recalls and frequency of consumption reported in Food Propensity Questionnaires (FPQs). Median exposure was estimated to be within safe levels for all population groups. However, 6.6% (n = 143) of the consumers exceeded the Acceptable Daily Intake (ADI) of nitrite (0.07 mg/kg bw/day), of which 20.3% were children aged 0-9 years (N = 29) (15.3% of all children participants in the study, N = 190). In total, pork meat was the major contributor (41.5%), followed by turkey meat (32.7%) and sausages (23.8%), although contribution variations were found among age groups. The outcomes are of public health concern, especially exposure among children, and future research is warranted to evaluate possible associations with health effects, by using more refined occurrence data if available.

Keywords: Greece; MPLs; dietary exposure; dietary intake; food additives; food group contribution; meat consumption; nitric compounds; processing; risk.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Diet
  • Female
  • Health Surveys
  • Humans
  • Male
  • Meat / analysis
  • Meat Products* / analysis
  • Nitrates
  • Nitrites* / adverse effects
  • Nitrogen Oxides
  • Risk Assessment

Substances

  • Nitrates
  • Nitrites
  • Nitrogen Oxides

Grants and funding

This research received no funding. The HNNHS was co-funded by the European Union (European Social Fund) and Greece (Ministry of Health) under the Operational Program “Human Resources Development 2007–2013”.