Identification of a novel HLA-A null allele, HLA-A*01:420N allele

HLA. 2023 Feb;101(2):143-145. doi: 10.1111/tan.14859. Epub 2022 Oct 31.

Authors

Magali Devriese^{1

2}, Cedric Usureau^{1

2}, Maryvonnick Carmagnat¹, Sephora Da Silva¹, Jean-Luc Taupin^{1

2}

Affiliations

¹ Laboratoire d'Immunologie et Histocompatibilité, Hôpital Saint Louis, Paris, France.
² HIPI, Human Immunology, Physiopathology and Immunotherapy, INSERM UMR976, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.

PMID: 36268577
DOI: 10.1111/tan.14859

Abstract

The novel HLA-A*01:420N allele has two changes in exon 4 leading to premature stop codon.

Keywords: HLA-A*01; nanotype sequencing; null allele; sequencing-based typing; soluble HLA.

© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
Base Sequence
Codon, Nonsense*
Exons / genetics
HLA-A Antigens* / genetics
Humans
Sequence Analysis, DNA

Substances

Codon, Nonsense
HLA-A Antigens