Transcriptomic and proteomic profiling of NaV1.8-expressing mouse nociceptors

Transcriptomic and proteomic profiling of Na_V1.8-expressing mouse nociceptors

Front Mol Neurosci. 2022 Oct 11:15:1002842. doi: 10.3389/fnmol.2022.1002842. eCollection 2022.

Manuela Schmidt¹, Julia Regina Sondermann¹, David Gomez-Varela¹, Cankut Çubuk^{2

3}, Queensta Millet⁴, Myles J Lewis^{2

3}, John N Wood⁴, Jing Zhao⁴

¹ Systems Biology of Pain, Division of Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria.
² Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
³ Centre for Translational Bioinformatics, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
⁴ Molecular Nociception Group, Wolfson Institute for Biomedical Research, Division of Medicine, University College London, London, United Kingdom.

No abstract available

Keywords: NaV1.8; dorsal root ganglia (DRG); nociceptor; pain; proteome; transcriptome.