Bottom-up assembly of viral replication cycles

Oskar Staufer; Gösta Gantner; Ilia Platzman; Klaus Tanner; Imre Berger; Joachim P Spatz

doi:10.1038/s41467-022-33661-7

Bottom-up assembly of viral replication cycles

Nat Commun. 2022 Nov 2;13(1):6530. doi: 10.1038/s41467-022-33661-7.

Authors

Oskar Staufer^{1

2

3}, Gösta Gantner^{4

5}, Ilia Platzman^{6

7

8}, Klaus Tanner^{4

5}, Imre Berger^{6

9

10}, Joachim P Spatz^{6

4

7

8}

Affiliations

¹ Max Planck-Bristol Center for Minimal Biology, University of Bristol, 1 Tankard's Close, Bristol, BS8 1TD, UK. [email protected].
² Kennedy Institute of Rheumatology, University of Oxford, Roosevelt Drive, OX3 7FY, UK. [email protected].
³ Max Planck School Matter to Life, Jahnstraße 29, 69120, Heidelberg, Germany. [email protected].
⁴ Max Planck School Matter to Life, Jahnstraße 29, 69120, Heidelberg, Germany.
⁵ Theological Seminary, Heidelberg University, Kisselgasse 1, 69117, Heidelberg, Germany.
⁶ Max Planck-Bristol Center for Minimal Biology, University of Bristol, 1 Tankard's Close, Bristol, BS8 1TD, UK.
⁷ Department for Cellular Biophysics, Max Planck Institute for Medical Research, Jahnstraße 29, 69120, Heidelberg, Germany.
⁸ Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM), University of Heidelberg, Im Neuenheimer Feld 225, 69120, Heidelberg, Germany.
⁹ School of Biochemistry, Biomedical Sciences, University of Bristol, 1 Tankard's Close, Bristol, BS8 1TD, UK.
¹⁰ Bristol Synthetic Biology Centre BrisSynBio, University of Bristol, 4 Tyndall Ave, Bristol, BS8 1TQ, UK.

Abstract

Bottom-up synthetic biology provides new means to understand living matter by constructing minimal life-like systems. This principle can also be applied to study infectious diseases. Here we summarize approaches and ethical considerations for the bottom-up assembly of viral replication cycles.

Bottom-up assembly of viral replication cycles

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