A recommendation on the teaching of Michaelis-Menten kinetics in biochemistry courses

Biochem Mol Biol Educ. 2023 Jan;51(1):39-43. doi: 10.1002/bmb.21689. Epub 2022 Nov 7.

Abstract

Most textbooks and lecturers present Michaelis-Menten kinetics using the equation v = Vmax [S]/(Km + [S]). There are advantages to presenting this relationship in a slightly different form, namely v = Vmax /{1 + (Km /[S])}. We articulate advantages for single-substrate reactions and extend the formalism to include the three classes of bi-substrate reactions.

Keywords: Michaelis-Menten; kinetics; pedagogy.

MeSH terms

  • Algorithms*
  • Biochemistry* / education
  • Enzymes / metabolism
  • Kinetics

Substances

  • Enzymes