Severe triple vessel disease secondary to IgG4-related coronary periarteritis

J Card Surg. 2022 Dec;37(12):5468-5471. doi: 10.1111/jocs.17187. Epub 2022 Nov 15.

Abstract

Background: Immunoglobulin G4-related disease is a rare systemic inflammatory disease that can lead to vascular manifestations such as periarteritis.

Case presentation: A 41-year-old man with stress angina was referred for coronary bypass surgery due to triple vessel coronary disease.

Conclusions: Operative findings revealed significant adhesions and dense peri-coronary and periaortic thickening, also involving the left internal mammary artery. The IgG4-associated disease was confirmed by aortic pathology. The stress angina subsequently improved with the initiation of treatment with prednisone and rituximab.

Keywords: IgG4-related disease; coronary artery disease; coronary vasculitis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angina Pectoris
  • Arteritis* / complications
  • Arteritis* / pathology
  • Coronary Artery Disease* / complications
  • Coronary Artery Disease* / pathology
  • Coronary Artery Disease* / surgery
  • Heart
  • Humans
  • Immunoglobulin G
  • Male

Substances

  • Immunoglobulin G