Bone marrow chimerism breaks the barrier to pancreatic islet transplantation

Cell Rep. 2022 Nov 15;41(7):111692. doi: 10.1016/j.celrep.2022.111692.

Abstract

In their recent Cell Reports paper, Chang and colleagues report on a successful strategy to achieve durable mixed hematopoietic chimerism that promotes the engraftment and long-term function of pancreatic islet allotransplants in fully immunocompetent mice without immunosuppression.

Publication types

  • Comment

MeSH terms

  • Animals
  • Bone Marrow
  • Bone Marrow Transplantation
  • Chimerism
  • Islets of Langerhans Transplantation*
  • Islets of Langerhans*
  • Mice