Neurologic Complications in Patients With Left Ventricular Assist Devices

Can J Cardiol. 2023 Feb;39(2):210-221. doi: 10.1016/j.cjca.2022.11.004. Epub 2022 Nov 15.

Abstract

Left ventricular assist device (LVAD) use has revolutionised the care of patients with advanced heart failure, allowing more patients to survive until heart transplantation and providing improved quality for patients unable to undergo transplantation. Despite these benefits, improvements in device technology, and better clinical care and experience, LVADs are associated with neurologic complications. This review provides information on the incidence, risk factors, and management of neurologic complications among LVAD patients. Although scant guidelines exist for the evaluation and management of neurologic complications in LVAD patients, a high index of suspicion can prompt early detection of neurologic complications which may improve overall neurologic outcomes. A better understanding of the implications of continuous circulatory flow on systemic and cerebral vasculature is necessary to reduce the common occurrence of neurologic complications in this population.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Heart Failure* / etiology
  • Heart Transplantation* / adverse effects
  • Heart-Assist Devices* / adverse effects
  • Humans
  • Risk Factors