Importance of NT-proBNP and conventional risk factors for prediction of death in older adults with and without diabetes mellitus- A report from the Atherosclerosis Risk in Communities (ARIC) study

Diabetes Res Clin Pract. 2022 Dec:194:110164. doi: 10.1016/j.diabres.2022.110164. Epub 2022 Nov 19.

Abstract

In this community-based cohort of 5861 individuals followed for median 7.2 years, the discriminatory ability of NT-proBNP alone in predicting mortality was similar to that of multiple conventional markers of risk in people without diabetes. In people with diabetes, NT-proBNP alone discriminated risk of mortality better than conventional risk factors.

Keywords: B-type natriuretic peptide; Biomarkers; Diabetes mellitus; Epidemiology; Mortality; Risk prediction.

MeSH terms

  • Aged
  • Atherosclerosis* / epidemiology
  • Biomarkers
  • Diabetes Mellitus* / epidemiology
  • Humans
  • Natriuretic Peptide, Brain
  • Peptide Fragments
  • Prognosis
  • Risk Factors

Substances

  • Natriuretic Peptide, Brain
  • Peptide Fragments
  • Biomarkers