Chiari I Malformation and Sleep-Disordered Breathing

Alexandria C Marino; Faraz Farzad; John A Jane Jr

doi:10.1016/j.nec.2022.08.005

Chiari I Malformation and Sleep-Disordered Breathing

Neurosurg Clin N Am. 2023 Jan;34(1):35-41. doi: 10.1016/j.nec.2022.08.005.

Authors

Alexandria C Marino¹, Faraz Farzad², John A Jane Jr³

Affiliations

¹ Department of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, USA; Department of Neurological Surgery, University of Virginia Health Sciences Center, PO Box 800212, Charlottesville, VA 22908, USA. Electronic address: [email protected].
² University of Virginia School of Medicine, Charlottesville, VA, USA.
³ Department of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, USA.

PMID: 36424062
DOI: 10.1016/j.nec.2022.08.005

Abstract

Sleep-disordered breathing (SDB) is a frequent symptomatic feature of pediatric Chiari I, reported in at least 24% of patients presenting to neurosurgeons. Here the epidemiology, natural history, pathophysiology, and diagnosis of SDB in Chiari I is reviewed. Diagnosis requires polysomnography, which should be pursued in young or symptomatic patients or those with prominent imaging findings. Review of case series of surgical decompression suggest that surgical decompression can improve SDB in selected patients.

Keywords: Chiari I; Pediatric neurosurgery; Posterior fossa decompression; Sleep apnea.

Publication types

Review

MeSH terms

Arnold-Chiari Malformation* / diagnosis
Arnold-Chiari Malformation* / diagnostic imaging
Child
Decompression, Surgical
Humans
Polysomnography / methods
Sleep Apnea Syndromes* / diagnosis
Sleep Apnea Syndromes* / epidemiology
Sleep Apnea Syndromes* / surgery