Human Fecal Mucin Glycosylation as a New Biomarker in Inflammatory Bowel Diseases

Inflamm Bowel Dis. 2023 Jan 5;29(1):167-171. doi: 10.1093/ibd/izac244.
No abstract available

Keywords: Crohn’s disease; diagnosis; human stools; inflammatory bowel syndrome; mucin glycans.

Plain language summary

For the first time, fecal mucins of Crohn’s disease patients were analyzed by mass spectrometry. Compared with control subjects, Crohn’s disease patients showed a significant decrease in sialylated glycans that we propose as new noninvasive tool for screening of intestinal diseases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers
  • Glycosylation
  • Humans
  • Inflammatory Bowel Diseases* / diagnosis
  • Mucins* / metabolism

Substances

  • Mucins
  • Biomarkers