Impact of Voltage Application on Degradation of Biorefractory Pharmaceuticals in an Anaerobic-Aerobic Coupled Upflow Bioelectrochemical Reactor

Int J Environ Res Public Health. 2022 Nov 21;19(22):15364. doi: 10.3390/ijerph192215364.

Abstract

Diclofenac, ibuprofen, and carbamazepine are frequently detected in the environment, where they pose a threat to organisms and ecosystems. We developed anaerobic-aerobic coupled upflow bioelectrochemical reactors (AO-UBERs) with different voltages, hydraulic retention times (HRTs), and types of electrode conversion, and evaluated the ability of the AO-UBERs to remove the three pharmaceuticals. This study showed that when a voltage of 0.6 V was applied, the removal rate of ibuprofen was slightly higher in the system with aerobic cathodic and anaerobic anodic chambers (60.2 ± 11.0%) with HRT of 48 h than in the control systems, and the removal efficiency reached stability faster. Diclofenac removal was 100% in the 1.2 V system with aerobic anodic and anaerobic cathodic chambers, which was greater than in the control system (65.5 ± 2.0%). The contribution of the aerobic cathodic-anodic chambers to the removal of ibuprofen and diclofenac was higher than that of the anaerobic cathodic-anodic chambers. Electrical stimulation barely facilitated the attenuation of carbamazepine. Furthermore, biodegradation-related species (Methyloversatilis, SM1A02, Sporomusa, and Terrimicrobium) were enriched in the AO-UBERs, enhancing pharmaceutical removal. The current study sheds fresh light on the interactions of bacterial populations with the removal of pharmaceuticals in a coupled system.

Keywords: applied voltages; bacterial community; bioelectrochemical reactor; electrode transition; pharmaceutical removal.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anaerobiosis
  • Bioreactors / microbiology
  • Carbamazepine
  • Diclofenac
  • Ecosystem
  • Ibuprofen
  • Pharmaceutical Preparations
  • Waste Disposal, Fluid*
  • Water Pollutants, Chemical* / analysis

Substances

  • Diclofenac
  • Ibuprofen
  • Water Pollutants, Chemical
  • Carbamazepine
  • Pharmaceutical Preparations

Grants and funding

This work was supported by the National Natural Science Foundation of China [grant No. 51968067], the Natural Science Foundation of Xinjiang Uygur Autonomous Region of China [grant No. 2018D01C044], State Key Laboratory of Pollution Control and Resource Reuse Foundation, [grant No. PCRRF19013], and State Key Joint Laboratory of Environment Simulation and Pollution Control, [grant No. 22K01ESPCT].