Case report: Reversible encephalopathy associated with liposomal amphotericin B in a patient with cryptococcal meningitis

Front Neurol. 2022 Nov 9:13:1019137. doi: 10.3389/fneur.2022.1019137. eCollection 2022.

Abstract

Liposomal amphotericin B (L-AMB) is an anti-fungus medicine that has fewer side effects than traditional amphotericin B (AMB). Neurotoxicity of L-AMB has rarely been observed, and only one case of leukoencephalopathy during intravenous L-AMB has been reported. Herein, we described a patient with cryptococcal meningitis presenting with late-onset reversible encephalopathy associated with liposomal amphotericin B.

Keywords: cryptococcal meningitis; encephalopathy; leukoencephalopathy; liposomal amphotericin B; neurotoxicity.

Publication types

  • Case Reports